Dental Journal of Advance Studies

Baljeet Singh

Abstract

No Abstract.

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Baljeet Singh ¹, Avnika Garg ¹, Rahul K. Garg ²

Affiliations
1 Department of Periodontics, Bhojia Dental College and Hospital, Distt. Solan, Himachal Pradesh, IN
2 IIM Ahmadabad, IN

Abstract

Aggressive periodontitis, which encompasses a number of clinical entities, probably results from the mobilization of tissue's destructive mechanisms which are common to most forms of periodontal diseases. The unique attributes of the disease process are due to the virulence of the pathogens and the host susceptibility may be due to the heritable or acquired susceptibility factors, which permit expression of periodontitis at a relatively younger age.

Keywords

Periodontitis, Aggressive Periodontitis, Periodontal Diseases.

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Baljeet Singh ¹, Avnika Garg ¹, Nandini Nayyar ¹, Alka Sharma ¹

Affiliations
1 Department of Periodontics, Bhojia Dental College and Hospital, Distt. Solan, Himachal Pradesh, IN

Abstract

Periodontal disease may be regarded as a range of different diseases for which certain individuals are at relatively high risk. Epidemiological and molecular studies of the oral microbial flora suggest, that although microbial factors are required for periodontal disease, they alone do not predict the presence or severity of periodontitis. So in high-risk patient groups, host factors appear to play an important role in susceptibility to periodontitis. In recent years elements of host susceptibility, such as immune response and systemic disease state, and other non-microbial environmental factors, such as smoking, have been shown to be important contributors to the disease expression. Thus, periodontitis represents a lifelong account of interactions between our genome, our behavior, and our environment.

Keywords

Genetics, Periodontium, Periodontitis.

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Baljeet Singh ¹, Shivani Bhickta ¹, Rajesh Gupta ¹, Sachin Goyal ¹, Ram Rattan Gupta ¹

Affiliations
1 Department of Periodontology, Bhojia Dental College and Hospital, Distt. Solan, Himachal Pradesh, IN

Abstract

The human inflammatory periodontal diseases are amongst the most common of chronic diseases. The predominant inflammatory cell (96%) within the healthy connective tissue and epithelium of the gingiva is polymorphonuclear leucocyte (PMNL). Periodontopathic bacteria in the gingivomucosal tissue may functionally activate PMNLs leading to an increased production of reactive oxygen species (ROS). Chronic inflammation subjects the nearby cells to elevated levels of free radicals (ROS) due to extracellular release from phagocytic cells. Antioxidants block the process of oxidation by neutralizing free radicals. In doing so, the antioxidant themselves become oxidized. Because of this, there is a constant need to replenish our antioxidant resources.

Keywords

Antioxidants, Periodontal Diseases, Reactive Oxygen Species.

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Isha Gargya ¹, Baljeet Singh ², Sanjay Talnia ³

Affiliations
1 Department of Orthodontics and Dentofacial Orthopaedics, Bhojia Dental College and Hospital, Himachal Pradesh, IN
2 Department of Periodontics, Bhojia Dental College and Hospital, Himachal Pradesh, IN
3 Department of Oral Surgery, Maharishi Markandeshwar College of Dental Sciences and Research, Haryana, IN

Abstract

Orthodontic tooth movement (OTM) is a complex process involving physiologic processes resulting in remodelling changes in the paradental tissues which are essential in orthodontic correction of tooth position. Medications have an influence on tooth movement and information on their consumption is essential to discuss treatment planning with patients. Various drugs either prescribed by the clinician or consumed by the patients enter the circulation and may be inhibitory, additive or synergise with the movement of teeth. Tooth movement through the remeodelling of bone is regulated by prostaglandins (PG) which play a direct role in bone resorption and is adversely affected by the use of NSAIDs (Non-Steroidal anti-inflammatory drugs) with research and clinical experience suggesting that their use slows down tooth movement due to a reduction in the number of osteoclastic cells. Since tooth movement is the key principle behind orthodontic treatment, any factor affecting the biologic response towards applied mechanical force is deemed to affect orthodontic treatment duration as well as efficacy. The purpose of this review article is to update the clinician on the role of most commonly used pharmaceutical drugs capable of affecting bone metabolism and rate of orthodontic tooth movement so that best therapeutic strategy can be formulated for an individual.

Keywords

NSAIDS, Orthodontic Therapy, Side Effect.

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