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Farhat, Karim
- Fluorescence Spectral Features of Blood Components of Pregnant Women
Abstract Views :207 |
PDF Views:67
Authors
Sandhanasamy Devanesan
1,
Mashael AlShebly
2,
Rudran Kalaivani
3,
Krishnan Sivaji
3,
Karim Farhat
4,
Mohamad Saleh AlSalhi
1,
Mohamed AlAtawi
2,
Danny Rabah
5,
Vadivel Masilamani
1
Affiliations
1 Laser Diagnosis of Cancers, College of Science, King Saud University, Riyadh 11451, SA
2 Department of Obstetrics and Gynecology, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh 11451, SA
3 Department of Nuclear Physics, University of Madras, Chennai 600 025, IN
4 Cancer Research Chair, College of Medicine, King Saud University, Riyadh 11451, SA
5 College of Medicine, King Saud University, Riyadh 11451, SA
1 Laser Diagnosis of Cancers, College of Science, King Saud University, Riyadh 11451, SA
2 Department of Obstetrics and Gynecology, College of Medicine, King Khalid University Hospital, King Saud University, Riyadh 11451, SA
3 Department of Nuclear Physics, University of Madras, Chennai 600 025, IN
4 Cancer Research Chair, College of Medicine, King Saud University, Riyadh 11451, SA
5 College of Medicine, King Saud University, Riyadh 11451, SA
Source
Current Science, Vol 113, No 03 (2017), Pagination: 457-461Abstract
During pregnancy, women experience various metabolic and hormonal changes that contribute to foetal development. These changes are investigated in the present study in terms of fluorescent biomolecules found in blood using synchronous fluorescence spectroscopy. Comparing a set of blood samples of 14 pregnant women against age-adjusted controls, it could be seen that the amino acid tryptophan is approximately twofold higher in blood plasma of pregnant women (P < 0.1), while the metabolite flavin adenine dinucleotide is approximately 25% lower. Further, the essential oxygen-carrying protein in the haemoglobin, porphyrin, is 80% higher in pregnant women. When these results were compared with the spectral features of blood components of patients with thalassaemia, it was found that erythrocytes had approximately 25% less haemolysis during the tenure of pregnancy.Keywords
Fluorescent Biomolecules, Pregnancy, Red Blood Cells, Synchronous Fluorescence Spectra.Full Text
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