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Chitosan Nanoparticles as a Carrier for Mentha longifolia Extract:Synthesis, Characterization and Antifungal Activity


Affiliations
1 Botany and Microbiology Department, College of Science, King Saud University, Riyadh 1145, Saudi Arabia
2 Plant Pathology Research Institute, Agricultural Research Center, Giza 12619, Egypt
3 Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh 11495, Saudi Arabia
4 Department of Biology, Princess Nourah Bint Abdulrahman University, Riyadh 11474, Saudi Arabia
 

A recent study was aimed at determining the antifungal activity of chitosan in both its natural and nanopa rticle forms. The present study reports on the prepa ration and characterization of ch itosan nanop articles and chitosan nanoparticle-incorporated Mentha longifolia. The size of the chitosan nanoparticles was 157 nm, and the mint extraction nanoparticles at concen trat ions of 5%, 10% and 20% were 142, 105 and 63 nm respectively. The surfaces of the chi tosan nanoparticles had a positive charge of approximately 33.2 mV, and the mint extract chitosan nanoparticles at 5%, 10% and 20% had charges of approximately 37.5, 36.9 and 36.1 mV respectively. The chitosan nanoparticles had a maximum encapsulation efficiency of 92% at a mint extract concentration of 20%. Mint extract incorporation into chitosan nanoparticles resulted in increased antifungal effects against mycelium growth of A. niger.

Keywords

Antifungal Activity, Characterization, Chitosan Nanoparticles, Mentha longifolia, Synthesis.
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  • Chitosan Nanoparticles as a Carrier for Mentha longifolia Extract:Synthesis, Characterization and Antifungal Activity

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Authors

Abd El-Aziz Abeer Ramadan Mohamed
Botany and Microbiology Department, College of Science, King Saud University, Riyadh 1145, Saudi Arabia
Al-Othman Monira Rashed
Botany and Microbiology Department, College of Science, King Saud University, Riyadh 1145, Saudi Arabia
Mohamed Abobakr Mahmoud
Plant Pathology Research Institute, Agricultural Research Center, Giza 12619, Egypt
Shereen Mohamed Shehata
Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh 11495, Saudi Arabia
Nahla Shazli Abdelazim
Department of Biology, Princess Nourah Bint Abdulrahman University, Riyadh 11474, Saudi Arabia

Abstract


A recent study was aimed at determining the antifungal activity of chitosan in both its natural and nanopa rticle forms. The present study reports on the prepa ration and characterization of ch itosan nanop articles and chitosan nanoparticle-incorporated Mentha longifolia. The size of the chitosan nanoparticles was 157 nm, and the mint extraction nanoparticles at concen trat ions of 5%, 10% and 20% were 142, 105 and 63 nm respectively. The surfaces of the chi tosan nanoparticles had a positive charge of approximately 33.2 mV, and the mint extract chitosan nanoparticles at 5%, 10% and 20% had charges of approximately 37.5, 36.9 and 36.1 mV respectively. The chitosan nanoparticles had a maximum encapsulation efficiency of 92% at a mint extract concentration of 20%. Mint extract incorporation into chitosan nanoparticles resulted in increased antifungal effects against mycelium growth of A. niger.

Keywords


Antifungal Activity, Characterization, Chitosan Nanoparticles, Mentha longifolia, Synthesis.

References





DOI: https://doi.org/10.18520/cs%2Fv114%2Fi10%2F2116-2122