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The 2017 Nobel Prize in Chemistry has been awarded to Jacques Dubochet, Joachim Frank and Richard Henderson for developing electron cryomicroscopy (cryoEM) for high-resolution determination of biological macromolecules in solution. It has long been realized that electron microscopy has the potential to reveal atomic details of macromolecules and this year's award is reflective on the various developments that have been made on specimen preparation, theoretical and computational approaches and detectors over the past four decades.
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