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Anaesthetic Implications for the Patient with Osteogenesis Imperfecta
Osteogenesis imperfercta (OI), is an autosomal dominant genetic disorder of connective tissue associated with blue sclera, dental abnormalities, frequent fractures, progressive hearing loss, and a positive family history. Anaesthetic implication of OI includes difficult intubation, platelet dysfunction, cardiovascular abnormalities like mitral valve prolapse, tendency to develop malignant hyperthermia and problems with positioning of patient due to brittle bones.
Osteogenesis Imperfecta, Anaesthetic Implications.
- Karabiyik L, Parpucu M, Kurtipek O. Total intravenous anaesthesia and the use of an intubating laryngeal mask in a patient with Osteogenesis Imperfecta. Acta Anaesthesiology Scand 2002; 46:618- 19.
- Sillence DO, Senn A, Danks DM. Genetic heterogeneity in osteogenesis imperfecta. Journal of Medical Genetics 1979;16: 101-116.
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