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Tiwari, Preeti
- Antimicrobial Activity of Ashwagandharishta Prepared by Traditional and Modern Methods
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Authors
Affiliations
1 Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar (U. P.), IN
1 Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar (U. P.), IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 4, No 3 (2014), Pagination: 115-117Abstract
In the present investigation, different types of test preparations of Ashwagandharishta as Ashwagandharishta-T, Ashwagandharishta-M prepared by traditional and modern methods respectively and marketed Ashwagandharishta were evaluated for antimicrobial activity against common human pathogens. It was observed that all the test preparations of Ashwagandharishta exhibited significant zone of inhibition against selected common human pathogens. The results indicate that all the test preparations of Ashwagandharishta as Ashwagandharishta-T, Ashwagandharishta-M and marketed Ashwagandharishta might be used as natural drug for the treatment of several infectious diseases caused by these organisms.Keywords
Ashwagandharishta-T, Ashwagandharishta-M, Antimicrobial Activity.
References
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- Antihyperlipidemic Potential of Balarishta Prepared by Traditional and Modern Methods in High Fat Diet Induced Hyperlipidemic Rats
Abstract Views :257 |
PDF Views:2
Authors
Affiliations
1 Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Uttar Pradesh, IN
1 Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Uttar Pradesh, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 4, No 1 (2014), Pagination: 7-11Abstract
The objective of the present study was to evaluate the lipid peroxidation activity and related antihyperlipidemic activity of Balarishta-T and Balarishta-M prepared by traditional and modern methods and its marketed formulation in high fat diet induced hyperlipidemic rats. The antioxidant activity of Balarishta-T and Balarishta-M was increased in concentration dependent manner. Balarishta-T and Balarishta-M inhibited the ferrous sulphate induced lipid peroxidation in a dose dependent manner and showed inhibitory concentration (IC50) value 196.61 μg/ml and 201.72 μg/ml respectively. Oral administration of Balarishta-T and Balarishta-M for nine weeks at the dose of 2 ml/kg significantly reduced serum cholesterol, serum LDL and serum triglycerides while showed significant rise in serum HDL as compared to high fat diet fed control group. Marketed Balarishta also showed significant decrease in serum cholesterol, serum LDL, serum triglycerides and showed significant rise in serum HDL. Atorvastatin (1.2 mg/kg, p.o.) was used as standard antihyperlipidemic drug. Both types of Balarishta as Balarishta-T and Balarishta-M showed significant reduction in atherogenic index as compared to high fat diet fed control group which strongly supports antiatherosclerotic property of Balarishta.Keywords
Balarishta, Lipid Per Oxidation, Atherogenic Index, Antihyperlipidemic Activity, Atorvastatin.References
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- Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) ischolar_main. Indian Journal of Experimental Biology 2000;38:607-609.
- Mishra S. Bhaisazya Kalpana Vigyan. Varanasi, India: Chaukambha Surbharati Prakashan; 2005.p. 253-254.
- Alam M, Radhamani S, Ali U and Purushottam KK. Microbiological Screening of Dhataki flowers. Journal of Research in Ayurveda and Siddha 1984; 2(4):371-375.
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- Evaluation of Diuretic Potential of Amritarishta Prepared by Traditional and Modern Methods in Experimental Albino Rats
Abstract Views :183 |
PDF Views:1
Authors
Affiliations
1 Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Uttar Pradesh, IN
1 Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar, Uttar Pradesh, IN