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Authors
Affiliations
1 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS -413736, IN
2 Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Nashik, M.S, IN
3 Department of Pharmaceutical Chemistry, S.N.D. College of Pharmacy, Yeola, Dist-Nashik, MS, IN
4 Department of Pharmaceutical Sciences and Research, Bhagwant University, Ajmer, Rajasthan, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 1, No 4 (2011), Pagination: 93-96
Abstract
Mercaptooxadiazole is a five membered heterocyclic system consists of two nitrogen and one oxygen atoms along with acidic thiol group. As it increases the acidity of the titled compounds. It can be easily synthesized from hydazides using potassium hydroxide in presence of carbon disulphide. Mercaptooxadiazoles posses wide spectrum of biological activities like antibacterial, antifungal, antiviral, anti-inflammatory, anticonvulsant, antidepressant, antihypertensive, analgesic, and hypoglycemic properties. The present review is an attempt made to reveal the therapeutic and synthetic profiles of the mercaptooxadiazole ring.
Keywords
Mercaptooxadiazole, Synthesis, Biological Evaluation.
