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Authors
Affiliations
1 Department of Chemistry, Zabid Education College, Hudaiadah University, YE
2 Gulbarga University, Gulbarga, Karnataka, IN
3 Department of Medical Laboratory, Ekra Collage, YE
4 Department of Medical Laboratory, Al-wahda University, YE
5 Department of Microbiology, Medical College, Taiz University, YE
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 6, No 4 (2016), Pagination: 240-245
Abstract
Aim: To determine the seroprevalence of toxoplasmosis and its associated risks factors among pregnant women and to assess the relation of some abnormalities and infection with Toxoplasmosis in Alkaeda province ibb city. Methodology: This prospective study was conducted at Alkaeda Hospital, over a 6 months period (March' 2016 to August' 2016). The study was approved by the Alrahma Medical Collage and written informed consents were obtained from the patients. The study group comprised pregnant women. Samples were tested for anti-Toxoplasma IgG and IgM antipodies by using OnSite Toxo IgG/IgM Rapid Test-Cassette. The On Site Toxo IgG/IgM Rapid Test is a lateral flow chromatographic immunoassay for the simultaneous detection and differentiation of IgG and IgM anti-Toxoplasma Gondii (T. gondii) in human serum or plasma. This kit is intended to be used as a screening test and as an aid in the diagnosis of infection with T. gondii. Any reactive specimen with the On Site Toxo IgG/IgM Rapid Test must be confirmed with alternative testing method(s) and clinical findings. Results: In the present study found that 13 sample (13%) were seropositive and 87 cases (87%) were seronegative for Toxoplasma specific IgG antibody and 4 samples (4%) were seropositive and 96 samples (96%) were seronegative for toxoplasma specific IgM antibody. The distribution of positive serum samples among the different age groups for anti-Toxoplasma gondii IgG and IgM showed that pregnant woman of the age group 23-30 years had the highest percentage (17.78 % and 6.68%) of positive results respectively. In present study of all cases,71 living in village which 4 (13.8%) cases of them were detected as IgG and 3(3.5) cases of them were detected as IgM. Of all cases 68 had history of contact with cat which 10(14.7) cases of them were detected as IgG positive and 4(5.9) cases of them were detected as IgM. In the present study showed that the seropositivity of Toxoplasma in relation to the number of times the antenatal woman experienced BOH revealed that the highest percentages (13.20%) of positivity was noted among women with a history of one BOH and seropositive cases were distributed in relation to the type of BOH revealed that Abortion (66.67%) was the commonest form of pregnancy wastage.
Keywords
Prevalence of Toxoplasmosis among Pregnant Women and Risk Factors.
