Asian Journal of Research in Pharmaceutical Sciences

A. B. Darekar ¹, S. Zope Janhavi ¹, R. B. Saudagar ²

Affiliations
1 Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN

Abstract

The world pharmaceutical industry has been changing profoundly in the last decade. Intensive globalization, increased competitiveness and the fight for global market shares create new challenges for pharmaceutical companies. Fast globalization definitively reinforces the consolidation of the world Pharmaceutical industry . The current shift in the marketing strategy is work by multinational Pharmaceutical Companies. It is now High - end development that is being carried out by leading companies. And, increasingly, other companies are finding themselves competing against, or working with, new innovation - based companies. My study focuses on objectives, importance, levels, theories, functions and types of pharmaceutical management and also pharmaceutical marketing, difference between general marketing and pharmaceutical marketing. Also study the overlook on Global Pharma Industry and Indian Pharma Industry. In this study the top 50 companies in 2009 and 2014 year are listed out. Also OTC segments and Pharmaceutical Policy are included in this article.

Keywords

Objectives, Importance, Functions, Difference between General Marketing and Pharmaceutical Marketing, Top 50 Companies in 2009 and 2014, OTC, Pharmaceutical Policy.

Full Text

     

L. Sonawane Pradnya ¹, A. B. Darekar ¹, R. B. Saudagar ²

Affiliations
1 Department of Pharmaceutics, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN

Abstract

The recent patented literature has concluded that there is an increasing interest in the novel dosage forms which retained in stomach for a longer period of time. Bilayer floating drug delivery system is new era for development of controlled release formulation. Bilayer floating drug delivery system is combined principle of bilayer technology as well as floating tablet is suitable for two incompatible drugs. The dosage form contains one sustain release layer and other is immediate layer. The immediate release layer is used to maintain dose. The floating dosage form can be prepared as tablet, capsule by adding suitable ingredients as well as adding gas generating agents.

Keywords

Gastroretentive Dosage Forms, Bilayer Floating Drug Delivery System, Immediate Layer, Control Release Layer.

Full Text

     

T. V. Kadam ¹, A. B. Darekar ¹, S. B. Gondkar ², R. B. Saudagar ³

Affiliations
1 Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
2 Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, IN

Abstract

In these studies describes a simple, accurate, precise and cost effective UV-visible spectrophotometric method for the estimation of Azelaic acid in pure and pharmaceutical formulations. The method is based on the measurement of absorbance of Azelaic acid solution in Phosphate buffer pH 6.8 at 204nm in the wavelength range of 200-400nm. The method obeys Beer's Lambert's law in the selected concentration range10-50 μg/ml in selected media. The slope, intercept and correlation coefficient were also calculated. Results of percentage recovery study shows that the method was not affected by the presence of common excipients in tablets. The parameters like linearity, precision, accuracy, sensitivity study i.e. limit of detection and limit of quantitation were studied according to International Conference on Harmonization (ICH) guidelines. The developed method was validated in terms of accuracy, precision, linearity, limit of detection and limit of quantitation which proves suitability of proposed method for routine estimation of Azelaic acid in pure and pharmaceutical formulations.

Keywords

UV-Visible Spectrophotometer, Method Development, Azelaic Acid.

Full Text