Asian Journal of Research in Pharmaceutical Sciences

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In vitro Antioxidant Activity of Premna serratifolia Linn


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1 P.G .Department of Biochemistry, Meenakshi Chandrasekaran College of Arts And Science, Pattukkottai-614 626, Thanjavur, Tamil Nadu, India
     

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The aim of this study was to investigate the antioxidant effect of Premna serratifolia Linn . The antioxidant activity was evaluated by various antioxidant assays, including 1, 1-diphenyl-2- picrylhydrazyl (DPPH), 2, 2’-azino-bis (3- ethylbenzthiazoline-6-sulfonic acid) (ABTS), and hydrogen peroxide scavenging method. The antioxidant activities were compared to standard antioxidant ascorbic acid. Premna serratifolia Linn wood extract showed a significant antioxidant activity in DPPH, ABTS and H2O2 scavenging methods. The findings of the present study suggest that Premna serratifolia Linn could be a potential source of natural antioxidant that could have greater importance as therapeutic agent in preventing or slowing oxidative stress related degenerative diseases.

Keywords

Premna Serratifolia Linn, Antioxidant Activity.
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  • In vitro Antioxidant Activity of Premna serratifolia Linn

Abstract Views: 608  |  PDF Views: 75

Authors

P. Muthukumaran
P.G .Department of Biochemistry, Meenakshi Chandrasekaran College of Arts And Science, Pattukkottai-614 626, Thanjavur, Tamil Nadu, India
S. Salomi
P.G .Department of Biochemistry, Meenakshi Chandrasekaran College of Arts And Science, Pattukkottai-614 626, Thanjavur, Tamil Nadu, India
R. Umamaheshwari
P.G .Department of Biochemistry, Meenakshi Chandrasekaran College of Arts And Science, Pattukkottai-614 626, Thanjavur, Tamil Nadu, India

Abstract


The aim of this study was to investigate the antioxidant effect of Premna serratifolia Linn . The antioxidant activity was evaluated by various antioxidant assays, including 1, 1-diphenyl-2- picrylhydrazyl (DPPH), 2, 2’-azino-bis (3- ethylbenzthiazoline-6-sulfonic acid) (ABTS), and hydrogen peroxide scavenging method. The antioxidant activities were compared to standard antioxidant ascorbic acid. Premna serratifolia Linn wood extract showed a significant antioxidant activity in DPPH, ABTS and H2O2 scavenging methods. The findings of the present study suggest that Premna serratifolia Linn could be a potential source of natural antioxidant that could have greater importance as therapeutic agent in preventing or slowing oxidative stress related degenerative diseases.

Keywords


Premna Serratifolia Linn, Antioxidant Activity.

References