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Evaluation of Stability Study of Ayurvedic Formulation Vasavaleha


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1 SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur (CG) 495 007, India
     

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Physic-chemical parameters and residual drug content of vasavaleha (AVB, AVB-1 and AVB-2) was measured at accelerated temperature. Results showed that no change was noticed in color, odor ant taste of AVB (prepared vasavaleha) up to storage of 180 days while at the same temperature after 120 days no changes were observed in odor of AVB-1 and AVB-2 whereas color becomes blackish brown to yellowish brown and taste turns to bitter. In pH, slight changes were noticed in all the formulations. Moisture content at 0 day of AVB was 3.75% which reduced after 60 days to 3.74% and after 120 days it was 3.72% while after 180 days it was found the same 3.72%. Same results were noticed during the stability study of AVB-1 and AVB-2 except that their % moisture content was not found constant up to 180 days storage. The percent residual drug content of prepared (AVB) vasavaleha was found 94.15% and 92.11%, 92.15% for AVB-1 andAVB-2 after 180 days at 40±1° C while 98.05%, 98.21%, 98.08% was estimated after 60 days at 40±1° C respectively for AVB, AVB-1 and AVB-2.
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  • Evaluation of Stability Study of Ayurvedic Formulation Vasavaleha

Abstract Views: 419  |  PDF Views: 87

Authors

Bharti Ahirwar
SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur (CG) 495 007, India

Abstract


Physic-chemical parameters and residual drug content of vasavaleha (AVB, AVB-1 and AVB-2) was measured at accelerated temperature. Results showed that no change was noticed in color, odor ant taste of AVB (prepared vasavaleha) up to storage of 180 days while at the same temperature after 120 days no changes were observed in odor of AVB-1 and AVB-2 whereas color becomes blackish brown to yellowish brown and taste turns to bitter. In pH, slight changes were noticed in all the formulations. Moisture content at 0 day of AVB was 3.75% which reduced after 60 days to 3.74% and after 120 days it was 3.72% while after 180 days it was found the same 3.72%. Same results were noticed during the stability study of AVB-1 and AVB-2 except that their % moisture content was not found constant up to 180 days storage. The percent residual drug content of prepared (AVB) vasavaleha was found 94.15% and 92.11%, 92.15% for AVB-1 andAVB-2 after 180 days at 40±1° C while 98.05%, 98.21%, 98.08% was estimated after 60 days at 40±1° C respectively for AVB, AVB-1 and AVB-2.

References