Asian Journal of Research in Pharmaceutical Sciences

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Activity of Quinazoline Derivatives:A Review


Affiliations
1 Department of Pharmaceutical Chemistry, MET’S Institute of Pharmacy, Bhujbal Knowledge City, Adgaon, Nashik-422 003. Savitribai Phule Pune University, Maharashtra, India
     

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A number of substituted quinazoline are known for their pharmacological importance, Literature indicate that derivatives consist of variety of pharmacological activity activities like anti-inflammatory, analgesic, anti-microbial, CNS depressant and anti-tubercular, anti-hypertensive anti-tumor activities have reported also. Current review is focusing on specific pharmacological activity anticonvulsant, anti-inflammatory, anti-hypertensive, anti- proliferative.

Keywords

Quinazolin, Anti-Cancer, Anti-Inflammatory, Anti-Microbial, Anti-Hypertensive.
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  • Mohamed F. Zayed, PhD, New fluorinated quinazolinone derivatives as anticonvulsant agents, Journal of Taibah University Medical Sciences 2014, 9(2), 104-109

  • Saleh K. Ihmaid .1, Hany E. A. Ahmed Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor,Molecule, January 2017

  • Niraj Kumar S, Alpana J. Asnani, Bhushan R. Synthesis and pharmacological evaluation of spiroquinazolinone as anti-inflammatory and Analgesic Agents. International Journal of Advanced Research (2013), Volume 1, Issue 6, 445-450

  • Niraj Kumar S, Alpana J. Asnani, Bhushan R. Synthesis and pharmacological evaluation of spiroquinazolinone as antiinflammatory and Analgesic Agents. International Journal of Advanced Research (2013), Volume 1, Issue 6, 445-450

  • Hurmath. S, Gayam. R, Aravazhi T. Synthesis and in vitro anti-tumor activity of some novel 2, 3- Disubstituted quinazoline 4(3H)-one derivatives. Journal of Applied Pharmaceutical Science Vol. 3 (10), pp. 136-140, October, 2013.

  • Fadhil Lafta Faraj, Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells. The Scientific World Journal Volume 2014, 15 pages( review 212096) 2014


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  • Activity of Quinazoline Derivatives:A Review

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Authors

D. D. Rishipathak
Department of Pharmaceutical Chemistry, MET’S Institute of Pharmacy, Bhujbal Knowledge City, Adgaon, Nashik-422 003. Savitribai Phule Pune University, Maharashtra, India
A. B. Kokate
Department of Pharmaceutical Chemistry, MET’S Institute of Pharmacy, Bhujbal Knowledge City, Adgaon, Nashik-422 003. Savitribai Phule Pune University, Maharashtra, India
K. S. Madhawai
Department of Pharmaceutical Chemistry, MET’S Institute of Pharmacy, Bhujbal Knowledge City, Adgaon, Nashik-422 003. Savitribai Phule Pune University, Maharashtra, India

Abstract


A number of substituted quinazoline are known for their pharmacological importance, Literature indicate that derivatives consist of variety of pharmacological activity activities like anti-inflammatory, analgesic, anti-microbial, CNS depressant and anti-tubercular, anti-hypertensive anti-tumor activities have reported also. Current review is focusing on specific pharmacological activity anticonvulsant, anti-inflammatory, anti-hypertensive, anti- proliferative.

Keywords


Quinazolin, Anti-Cancer, Anti-Inflammatory, Anti-Microbial, Anti-Hypertensive.

References