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Preparation and In Vitro Charactersation of Fast Disintigrating Tablets of Cimetidine


Affiliations
1 St.Johns College of Pharmaceutical Sciences, Yerakota, Yemmiganur , Kurnool (Dist) , Andhra Pradesh, India
2 Department of Pharmaceutics, OU Ph.D Scholar, Osmania University, Hyderabad, India
     

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The present study was carried out to develop Fast Disintegration Tablets of Cimetidine. Kollidon, Vivasol, Tulsion 330 powder were used as Super Disintegrants. The blend of all the formulations showed good flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations F7 formulation showed maximum % drug release i.e., 98.62% in 60 min hence it is considered as optimized formulation.

Keywords

Cimetidine, Kollidon, Vivasol, Tulsion 330 and Fast Disintegration Tablets.
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  • Preparation and In Vitro Charactersation of Fast Disintigrating Tablets of Cimetidine

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Authors

N. M. Vageesh
St.Johns College of Pharmaceutical Sciences, Yerakota, Yemmiganur , Kurnool (Dist) , Andhra Pradesh, India
D. Rafian
St.Johns College of Pharmaceutical Sciences, Yerakota, Yemmiganur , Kurnool (Dist) , Andhra Pradesh, India
U. Govindamma
St.Johns College of Pharmaceutical Sciences, Yerakota, Yemmiganur , Kurnool (Dist) , Andhra Pradesh, India
Ramya Sri Sura
Department of Pharmaceutics, OU Ph.D Scholar, Osmania University, Hyderabad, India

Abstract


The present study was carried out to develop Fast Disintegration Tablets of Cimetidine. Kollidon, Vivasol, Tulsion 330 powder were used as Super Disintegrants. The blend of all the formulations showed good flow properties such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations F7 formulation showed maximum % drug release i.e., 98.62% in 60 min hence it is considered as optimized formulation.

Keywords


Cimetidine, Kollidon, Vivasol, Tulsion 330 and Fast Disintegration Tablets.

References