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Analgesic Activity of Methanol Extract of Alpinia conchigera Griff by Acetic Acid Induced Writhing Method


Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, Bangladesh
     

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The present study was designed to investigate Analgesic activity of methanolic extract of Alpinia conchigera Griff, using Acetic Acid Induced Writhing method. Methanolic extract was administered intraperitoneally at doses of 250 mg/kg and 500 mg/kg to Young Swiss-albino mice. Methanol Extract of Alpinia conchigera Griff showed significant inhibition in pain response induced by thermal and mechanical stimuli in dose dependent manner. The obtained results provide promising baseline information for the potential use of these crude extract in the treatment of pain.

Keywords

Alpinia conchigera Griff, Analgesic, Acetic Acid, Writhing Method.
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  • Analgesic Activity of Methanol Extract of Alpinia conchigera Griff by Acetic Acid Induced Writhing Method

Abstract Views: 46  |  PDF Views: 2

Authors

Swati Paul
Department of Pharmacy, BGC Trust University, Chittagong, Bangladesh
Dibyajyoti Saha
Department of Pharmacy, BGC Trust University, Chittagong, Bangladesh

Abstract


The present study was designed to investigate Analgesic activity of methanolic extract of Alpinia conchigera Griff, using Acetic Acid Induced Writhing method. Methanolic extract was administered intraperitoneally at doses of 250 mg/kg and 500 mg/kg to Young Swiss-albino mice. Methanol Extract of Alpinia conchigera Griff showed significant inhibition in pain response induced by thermal and mechanical stimuli in dose dependent manner. The obtained results provide promising baseline information for the potential use of these crude extract in the treatment of pain.

Keywords


Alpinia conchigera Griff, Analgesic, Acetic Acid, Writhing Method.