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Antiurolithic Activity of Aqueous Extract on Roots and Seeds of Plectranthus tomentora on Ethylene Glycol Induced kidney Stones in Male Albino Rats


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1 Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist, India
     

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The kidney stone is one of the most widely spreading renal disorders in the world. The present study was undertaken to evaluate the efficacy of Plectranthus tomentora in reducing the growth of calcium oxalate stones in ethylene glycol induced model. Upon administration of Furosemide (20mg/kg), aqueous extract of ischolar_mains and seeds of Plectranthus tomentora (500 and 1000 mg/kg) on hyperoxaluria rats shows the significant activity in decrease kidney stones and serum levels (calcium, phosphorous, creatinine, urea) both not that as standard drug Furosemide.

Keywords

Plectranthus tomentora, Calcium Oxalate, Ethylene Glycol, Furosemide.
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  • Antiurolithic Activity of Aqueous Extract on Roots and Seeds of Plectranthus tomentora on Ethylene Glycol Induced kidney Stones in Male Albino Rats

Abstract Views: 219  |  PDF Views: 0

Authors

Chandaka Madhu
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist, India
L. Harish
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist, India
K. Narsimha Reddy
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist, India
S. Sagar
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist, India
D. Soumya
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist, India
G. Pavan Kumar
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist, India

Abstract


The kidney stone is one of the most widely spreading renal disorders in the world. The present study was undertaken to evaluate the efficacy of Plectranthus tomentora in reducing the growth of calcium oxalate stones in ethylene glycol induced model. Upon administration of Furosemide (20mg/kg), aqueous extract of ischolar_mains and seeds of Plectranthus tomentora (500 and 1000 mg/kg) on hyperoxaluria rats shows the significant activity in decrease kidney stones and serum levels (calcium, phosphorous, creatinine, urea) both not that as standard drug Furosemide.

Keywords


Plectranthus tomentora, Calcium Oxalate, Ethylene Glycol, Furosemide.