Asian Journal of Research in Pharmaceutical Sciences

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Microsponges


Affiliations
1 Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, India
2 Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, India
     

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The drug delivery technology landscape has become highly competitive and rapidly evolving. More and more developments in delivery systems are being integrated to optimize the efficacy and cost-effectiveness of the therapy. Peptides, proteins and DNA-based therapeutics cannot be effectively delivered by conventional means. To control the delivery rate of active agents to a predetermined site in human body has been one of the biggest challenges faced by drug industry. Controlled release of drugs onto the epidermis with assurance that the drug remains primarily localized and does not enter the systemic circulation in significant amounts is an area of research that is successively done by the Microsponge delivery system. This review covers the advantages of Microsponges, their formulation and applications in pharmaceutical field.

Keywords

Microsponge, Controlled Release, Topical Drug Delivery, Oral Drug Delivery, Liquid-Liquid Suspension Polymerization.
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  • Microsponges

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Authors

D. M. Shinkar
Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, India
Bhushan S. Bhamare
Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, India
R. B. Saudagar
Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, India

Abstract


The drug delivery technology landscape has become highly competitive and rapidly evolving. More and more developments in delivery systems are being integrated to optimize the efficacy and cost-effectiveness of the therapy. Peptides, proteins and DNA-based therapeutics cannot be effectively delivered by conventional means. To control the delivery rate of active agents to a predetermined site in human body has been one of the biggest challenges faced by drug industry. Controlled release of drugs onto the epidermis with assurance that the drug remains primarily localized and does not enter the systemic circulation in significant amounts is an area of research that is successively done by the Microsponge delivery system. This review covers the advantages of Microsponges, their formulation and applications in pharmaceutical field.

Keywords


Microsponge, Controlled Release, Topical Drug Delivery, Oral Drug Delivery, Liquid-Liquid Suspension Polymerization.