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Phytochemical Screening and In-Vitro Athelmintic Activity of Seed Extracts of Plants Carum carvi of Family Apiaceae


Affiliations
1 Department of Pharmacy, Sunrise University, Alwar-301001 Rajasthan, India
2 SSTC, Junwani, Bhilai-490020, Chattisgarh, India
     

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The present research aimed at the in-vitro study of the anthelmintic activity of aqueous and ethanolic extracts of seeds of Carum carvi using Indian adult earthworms (Pheretima posthuma) at two different concentrations (10 and 20 mg/ml) in two different volumes 10ml and 15ml respectively. The study involved the determination of the time of paralysis and time of death of the worms. At the concentration of 20mg/ml in both volume i.e. 10ml and 15ml the Ethanolic extracts showed very significant activities as compared to the standard drug Albendazole at two different concentrations (10 and 20 mg/ml) volume taken 15ml. Ethanolic extract gives more effective result than aqueous extract when compare to standard. But aqueous extract also shows anthelmintic activity. In conclusion, aqueous and ethanolic extracts of seeds of Carum carvi as an anthelmintic have been confirmed and further studies are suggested to discover the active principles responsible for the activity.

Keywords

Carum carvi, Phytochemical, Anthelmintic, Pheretima posthuma, Albendazole.
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  • Phytochemical Screening and In-Vitro Athelmintic Activity of Seed Extracts of Plants Carum carvi of Family Apiaceae

Abstract Views: 31  |  PDF Views: 2

Authors

Shiba S. Morris
Department of Pharmacy, Sunrise University, Alwar-301001 Rajasthan, India
G. Jeyabalan
Department of Pharmacy, Sunrise University, Alwar-301001 Rajasthan, India
A. K. Jha
SSTC, Junwani, Bhilai-490020, Chattisgarh, India
Shekhar Verma
SSTC, Junwani, Bhilai-490020, Chattisgarh, India
Yashwant Swarnkar
SSTC, Junwani, Bhilai-490020, Chattisgarh, India

Abstract


The present research aimed at the in-vitro study of the anthelmintic activity of aqueous and ethanolic extracts of seeds of Carum carvi using Indian adult earthworms (Pheretima posthuma) at two different concentrations (10 and 20 mg/ml) in two different volumes 10ml and 15ml respectively. The study involved the determination of the time of paralysis and time of death of the worms. At the concentration of 20mg/ml in both volume i.e. 10ml and 15ml the Ethanolic extracts showed very significant activities as compared to the standard drug Albendazole at two different concentrations (10 and 20 mg/ml) volume taken 15ml. Ethanolic extract gives more effective result than aqueous extract when compare to standard. But aqueous extract also shows anthelmintic activity. In conclusion, aqueous and ethanolic extracts of seeds of Carum carvi as an anthelmintic have been confirmed and further studies are suggested to discover the active principles responsible for the activity.

Keywords


Carum carvi, Phytochemical, Anthelmintic, Pheretima posthuma, Albendazole.