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Authors
Affiliations
1 Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, Jalgaon Dist, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 3 (2010), Pagination: 714-715
Abstract
A simple, sensitive, accurate and precise UV Spectrophotometric method has been developed for quantitative determination of Tramadol Hydrochloride in bulk and tablet formulations. The UV-spectrum was scanned between 220 to 400 nm and 270.5 nm was selected as maximum wavelength for absorption. Tramadol shows molar absorptivity of 1.771×104 l/mol/cm and Sandell’s sensitivity 0.16927 mcg/Sq.cm/0.001-absorbance units. Beer’s law was obeyed in the concentration range of 15-170 μg/ml. Results of analysis were validated statistically and by recovery studies.
Keywords
Tramadol Hydrochloride, Tablet, Ultraviolet Spectrophotometric Estimation.