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Nazimuddin, Syed
- An Efficient Nickel Chloride Catalyzed Multi-Component Condensation of Indole with Carbonyl Compounds in PEG-400 as a Green Medium at Ambient Conditions
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1 Post Graduate and Research Centre, Dr. Rafiq Zakaria Campus, Maulana Azad College, Rauza Baugh, Aurangabad, 431001, IN
1 Post Graduate and Research Centre, Dr. Rafiq Zakaria Campus, Maulana Azad College, Rauza Baugh, Aurangabad, 431001, IN
Source
Asian Journal of Research in Chemistry, Vol 10, No 3 (2017), Pagination: 267-270Abstract
Bis (indolyl) methane derivatives were efficiently synthesized by the condensation reaction of various aromatic aldehydes and indole in presence of nickel chloride as a Lewis acid catalyst in PEG-400 as a recyclable green solvent at room temperature. The use of PEG-400 and nickel chloride offers improvements for the synthesis of bis (indoyl) methanes with regard to the yield of products, short reaction times and green aspects utilizing recyclable and non volatile medium and avoiding any volatile and hazardous organic solvent.Keywords
Bis (Indolyl) Methane, Nicke (II) Chloride, PEG-400.- Synthesis of 1,3,4-Oxadiazole
Abstract Views :210 |
PDF Views:5
Authors
Affiliations
1 P.G. and Research Centre, Maulana Azad College of Arts, Science and Commerce, Aurangabad, IN
1 P.G. and Research Centre, Maulana Azad College of Arts, Science and Commerce, Aurangabad, IN