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Desai, K.R.
- Eco-friendly Synthesis of Novel Fluorine Containing 1,3,4-oxadiazoles as Antibacterial and Antifungal Agents
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1 Department of Chemistry, Veer Narmad South Gujarat University, Surat -395 007
1 Department of Chemistry, Veer Narmad South Gujarat University, Surat -395 007
Source
Asian Journal of Research in Chemistry, Vol 6, No 5 (2013), Pagination: 486-489Abstract
Title compounds of 1,3,4-oxadiazoles derivatives by the ring closure reaction of m-fluorobenzoic acid hydrazide with an aromatic acid and alumina in presence of POCl3 under microwave irradiation. All the newly synthesized compounds were screened for their antibacterial activity against Gram-positive bacteria namely staphylococcus aureus, Bacillus subtilis and Gram-negative bacteria namely, Escherichia coli and Pseudomonas aeruginosa. All the synthesized compounds were also tested for their antifungal activity against fungi namely, Candida albicans.Keywords
2,5-disubstituted 1,3,4-oxadiazoles, Ring Closure Reaction, Antibacterial Activity, Antifungal Activity
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