Asian Journal of Research in Chemistry

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Clinical Study on Serum Zinc Levels in Patients with Acne Vulgaris


Affiliations
1 Department of Biochemistry, Gandhi Medical College & Gandhi Hospital, Secunderabad, Andhra Pradesh, India
2 Department of Dermatology, Gandhi Medical College & Gandhi Hospital, Secunderabad, Andhra Pradesh, India
     

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Objectives: To determine the serum zinc levels in young patients suffering from Acne vulgaris.
Methods: The study included 50 young female patients, aged between 13 and 19 years, suffering from Acne vulgaris (patients group) and 25 age matched healthy female attenders of patients without acne (control group). The zinc levels were measured in the serum obtained from the fasting blood of patients group and control group. Results: The serum zinc level was lower than normal in 50 out of 50 patients (100%), and in none out of 25 controls (0%). The mean zinc levels were significantly lower in patients with acne (24.4 ± 2.4μg /dl) than in controls (99.4 ± 4.5 µg/dl).
Conclusion: We conclude that zinc supplementation as an adjunctive therapy in acne patients with low serum zinc level may increase the success rate of acne treatment as zinc deficiency is one of the causes of this disease.

Keywords

Acne Vulgaris, Serum Zinc
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  • Clinical Study on Serum Zinc Levels in Patients with Acne Vulgaris

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Authors

Fouqiya Butool
Department of Biochemistry, Gandhi Medical College & Gandhi Hospital, Secunderabad, Andhra Pradesh, India
C. Rekha
Department of Biochemistry, Gandhi Medical College & Gandhi Hospital, Secunderabad, Andhra Pradesh, India
A. Gnaneswar Rao
Department of Dermatology, Gandhi Medical College & Gandhi Hospital, Secunderabad, Andhra Pradesh, India

Abstract


Objectives: To determine the serum zinc levels in young patients suffering from Acne vulgaris.
Methods: The study included 50 young female patients, aged between 13 and 19 years, suffering from Acne vulgaris (patients group) and 25 age matched healthy female attenders of patients without acne (control group). The zinc levels were measured in the serum obtained from the fasting blood of patients group and control group. Results: The serum zinc level was lower than normal in 50 out of 50 patients (100%), and in none out of 25 controls (0%). The mean zinc levels were significantly lower in patients with acne (24.4 ± 2.4μg /dl) than in controls (99.4 ± 4.5 µg/dl).
Conclusion: We conclude that zinc supplementation as an adjunctive therapy in acne patients with low serum zinc level may increase the success rate of acne treatment as zinc deficiency is one of the causes of this disease.

Keywords


Acne Vulgaris, Serum Zinc

References