Asian Journal of Pharmacy and Technology

Neha Meshram Ojha ¹, Mithlesh Ojha ¹, Ajay Singh ², Amit Alexander ¹, Ajazuddin ¹, Mukesh Sharma ¹

Affiliations
1 Rungta College of pharmaceutical sciences and research Kohka-Kurud, Bhilai, C.G, IN
2 GD Rungta College of Science and Technology Kohka-Kurud, Bhilai, C.G, IN

Abstract

Peptic ulcer disease is an imbalance between offensive and defensive gastric factors. This is a major cause of mortality in developing countries. This has attracted several scientists foe their research contributions to this area. Peptic ulcer disease is a serious gastrointestinal disorder that requires a well targeted therapeutic strategy. A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but clinical evaluation of these drugs has shown incidence of relapses, side effects and drug interactions. This has been the rational for the development of new antiulcer drugs and the novel formulations that extend to herbal drugs. Good scientific confirmation of traditional knowledge of drugs for treatment of various disorders has made herbal approach a scientific budding area of interest now days. This review article includes physiological aspects of peptic ulcer disease and list of herbal drugs which are used in the treatment of peptic ulcer. Here we have highlighted some of the important plants reported for their anti-ulcer and ulcer healing properties. Ayurvedic knowledge supported by modern science is necessary to isolate, characterise, and standardise the active constituents from herbal sources for antiulcer activity.

Keywords

Peptic Ulcer, Traditional Knowledge, Gastrointestinal Disorder, Novel Formulations, Drug Interactions.

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Ajay Singh ¹, Ragini Tiwari ¹, Prakriti Singh ¹, Vinay Sagar Verma ², Mukesh Sharma ², Amit Alexander ², Ajazuddin ²

Affiliations
1 GD Rungta College of Science and Technology, Kurud, Bhilai (Chhattisgarh), IN
2 Rungta College of Pharmaceutical Sciences and Research, Kurud, Bhilai (Chhattisgarh), IN

Abstract

An aeromycological study to identify and quantify allergenic fungi and their fluctuations was conducted at Bhilai city. The diversity of the aeromycoflora at different height in this study, based on the recovery of fungal propagules by the air-exposing-PDA plating method was conducted in rainy season. The study showed that the most prevalent (major components) fungal spores in the air on different heights (0-10feet,10-20and 20-40feets) in kohka-Bhilai city were Aspergillus spp. Alternaria spp. Curvularia spp. Rhizopus spp. Penecillin spp. fusarium spp. The abundant genera on different heights were Curvularia, Aspergillus, Alternaria. Curvularia spp. Aspergillus spp. were the most abundant fungal spore type collected throughout the period of study on different height in kohka-bhilai city.

Keywords

Aeromycoflora, Allergenic Fungi, Aspergillus, Alternaria, Curvularia.

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