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Rakha, Pankaj
- Anti - Inflammatory Potential of the Seeds of Ocimum basilicum Linn. in Rats
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Authors
Affiliations
1 Guru Jambheshwar University of Science and Technology, Hisar (Haryana), IN
1 Guru Jambheshwar University of Science and Technology, Hisar (Haryana), IN
Source
Asian Journal of Bio Science, Vol 5, No 1 (2010), Pagination: 16-18Abstract
In the present study, the effect of the seeds of the plant Ocimum basilicum Linn. on inflammation induced by histamine and prostaglandins was studied. A total of 60 rats divided in 10 groups were used in this study. The experimental design was approved by IAEC. The increase in paw edema served as the index of inflammation and was measured using digital vernier calipers after injecting various edemogens such as histamine and PGF2α. Petroleum ether fraction (400mg/kg, p.o) and ethanolic fraction (400mg/kg, p.o) of the seeds of Ocimum basilicum Linn. significantly inhibited the paw edema produced by histamine and PGF2-α. These findings reveal that the seeds of the plant Ocimum basilicum Linn. possesses potent anti-inflammatory activity.Keywords
Anti-Inflammatory, Histamine, Prostaglandins.
- Anti-Parkinsonian Effect of Aloe vera Juice in Rodents
Abstract Views :617 |
PDF Views:6
Authors
Milind Parle
1,
Pankaj Rakha
1
Affiliations
1 Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar (Haryana), IN
1 Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar (Haryana), IN
Source
Asian Journal of Bio Science, Vol 13, No 1 (2018), Pagination: 39-43Abstract
Parkinson disease is characterized by rigidity, tremors, shuffling gait and bradykinesia.At present, pharmacotherapy of Parkinsonism is limited mostly to symptomatic treatments that do not alter the course of the underlying disease. A number of medicines have been prescribed for treating this disorder particularly Levodopa. In Charak Sanhita, this disorder is named as Kampavata. Enormous numbers of compounds have been fractionated from plant sources for the treatment of Parkinson’s disease. In the present study, an attempt was made to evaluate the anti-parkinsonian effect of Aloe vera juice using different experimental models. The powerful anti-oxidant activity possessed by Aloe vera, when coupled with the observations of the present study such as significant reduction in rigidity, hypokinesia and tremors of animals in different experimental models suggest promising anti-parkinsonian potential of Aloe vera juice.Keywords
Rigidity, Tremors, Bradykinesia, Parkinsonism.References
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