Asian Journal of Bio Science

K. Gokulakrishnan ¹, P. Senthamilselvan ¹, V. Sivakumari ²

Affiliations
1 Department of Biochemistry, Marudu Pandiyar College, Thanjavur (T.N.), IN
2 Department of Environmental and Herbal Sciences, Tamil University, Thanjavur (T.N.), IN

Abstract

Liver regulates many important metabolic functions. Hepatic injury is associated with distoration of these metabolic functions. Thus liver disease remains one of the serious health problems. Inspite of tremendous studies in modern medicine, there are not much drugs available for the treatment of liver disorders. In the present study, paracetamol was used to induce the hepatic damage. Paracetamol, is a widely used analgesic and antipyretic drug. Oxidative stress is reported to play an important role in the pathogenesis of paracetamol – induced liver damage. The result confirm that Citrus aurantifolia possess a potential hepatoprotective activity.

Keywords

Liver, Paracetamol, Citrus aurantifolia and Phytochemicals.

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P. Senthamilselvan ¹, V. Sivakumari ²

Affiliations
1 Marudu Pandiyar College, Thanjavur (T.N.), IN
2 Department of Environmental and Herbal Sciences, Tamil University, Thanjavur (T.N.), IN

Abstract

Breast cancer is one of the most common cancers in developed and developing countries. In India, it is the second most frequent cancer, which is estimated to be 19.3% of total female cancer with age standardized rate 17.5 per 100,000.The exact cause of breast cancer is not completely known but presumably it represents a complex interplay of genetic susceptibility and environmental factors. Hematology, lipid and lipoproteins have also been associated with risk of breast cancer. The present study was carried out to investigate Total Cholesterol (TC), High Density Lipoprotein Cholesterol (HDL-C), Low Density Lipoprotein Cholesterol (LDLC), Triglycerides’ (TG), sodium, chloride, potassium, SGOT, SGPT, glucose, urea, uric acid and creatinine in female with breast cancer. In the study revealed significant difference between breast cancer and normal subject with respect to most of the biochemical parameter analyzed.

Keywords

Total Cholesterol, SGOT, SGPT, Breast Cancer.

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