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Authors
Affiliations
1 Department of Zoology, Kakatiya University, Warangal (A.P.), IN
Source
Asian Journal of Bio Science, Vol 5, No 1 (2010), Pagination: 77-79
Abstract
Acetyl cholinesterase (AChE) is an enzyme present in the synapses and myoneural junctions. The levels of the enzyme causes neuronal diseases. Many pollutants causes neuronal diseases to aquatic organisms. The objective of the study was to study the effect of pesticide ‘Kingdoxa’ in freshwater mussels Lamellidens Marginalis (Lamark). Therefore, the effect of sub lethal concentration of commonly used pesticide Kindoxa was studied on the Acetylcholine (ACh) and Acetylcholineserase (AChE) activity in foot, mantle and gill of a fresh water mussel, L. marginalis. To compare the effect of these pesticides on Ach and AChE activity, the mussels were exposed to sub-lethal concentration (Kindoxa 0.33 ppm) of pesticide for 48 hours. After the exposure, the animals were sacrificed tissues were isolated and processed for the estimation of Ach and AChE activity. When exposed to sublethal concentration of the pesticide, the activity levels of AChE was decreased and ACh content was increased in all the three tissues treated with Kindoxa. At tissue level inhibition was in the order of mantle > gill > foot. The inhibition of AChE and elevation of Ach content was higher in mussels exposed to Kindoxa. Therefore, it is possible that Kindoxa due to their inhibitory effect on the enzyme and ability to obstruct ACh hydrolysis cause its accumulation and ultimately lead to the disruption of nervous co-ordination and consequently death, in case of acute poisoning.
Keywords
Kindoxa, Acetylcholine, Acetyl Cholinesterase, L. marginalis.
