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Authors
Affiliations
1 Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam University for Women, Coimbatore (T.N.), IN
Source
Asian Journal of Bio Science, Vol 4, No 2 (2010), Pagination: 149-152
Abstract
The present study was carried out to evaluate the antioxidant status of three different extracts of Rhinacanthus nasutus leaves on the oxidant induced goat liver slices under in vitro conditions. The antioxidant potential of all the extracts were assessed by analysing the non-enzymic antioxidants. The extracts were also analysed for the extent of inhibition of lipid peroxidation in H2O2 induced goat liver slices. The results of the present study showed that the methanolic extract was found to contain highest amount of non-enzymic antioxidants followed by the aqueous extract and the chloroform extract. It is evident that Rhinacanthus nasutus leaf extracts offered efficient antioxidant defense in the goat liver slices, an in vitro model which simulates in vivo condition, when exposed to H2O2. Health benefits can be obtained from the leaves with decreased risk of disease as the leaves could prevent or protect the oxidative damage caused by environmentally benign oxidant hydrogen peroxide.
Keywords
Vitamin C, Vitamin E, Vitamin A and Reduced Glutathione, Free Radicals, Methanolic Extract, Lipid Peroxidation, Rhinacanthus nasutus.
